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NCT03120468
EARLY_PHASE1
Topiramate Augmenting Strategies for the Treatment of Alcohol Use Disorder
Sponsor: Nassima Ait-Daoud Tiouririne
View on ClinicalTrials.gov
Summary
This is a pilot study designed to evaluate the safety, tolerability of Topiramate (TPM) + N-Acetyl Cysteine (NAC) in combination versus Topiramate (TPM) + placebo for the treatment of alcohol use disorder (AUD).
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
17
Start Date
2017-05-01
Completion Date
2019-06-30
Last Updated
2026-05-27
Healthy Volunteers
No
Conditions
Interventions
DRUG
Topiramate and N-Acetyl Cysteine
Topiramate up to 200 mg/day and N-Acetyl Cysteine 600 mg twice a day for 12 weeks
DRUG
Topiramate and Placebo
Topiramate up to 200 mg/day and Placebo for 12 weeks
Locations (1)
UVA Center for Leading Edge Addiction Research
Charlottesville, Virginia, United States