Clinical Research Directory

Inclusion Criteria: * Female subjects of 18-45 years, with Postural Tachycardia Syndrome (POTS) as defined by a heart rate increase ≥30 bpm from supine within 10 min of standing or head-up tilt in the absence of orthostatic hypotension, with chronic symptoms (\> 6 months), and in the absence of other acute cause of orthostatic tachycardia. * Subjects able and willing to provide informed consent Exclusion Criteria: * Pregnancy. * Medical conditions that can explain postural tachycardia (e.g., dehydration, medications). * Patients who are bedridden or chair-ridden * Subjects taking any medication known to affect autonomic function or inflammatory markers (e.g. corticosteroids) who could not discontinue them before study participation. * Conditions associated with chronic inflammatory processes which in the investigator's opinion would affect the interpretation of the results. Examples may include smoking, diabetes, BMI\>30 kg/m2, current infections or cancer. * Other factors which in the investigator's opinion would prevent the subject from completing the protocol.