Clinical Research Directory
Browse clinical research sites, groups, and studies.
Breathing Exercises in Asthma Targeting Dysfunctional Breathing
Sponsor: Naestved Hospital
Summary
Dyspnoe can disable patients with asthma. Dysfunctional breathing (DB), resulting in dyspnoe, can mimic or exaggerate asthma. Around every forth patient with asthma have DB. Breathing exercises (BrEX) can improve asthma-related quality of live (QOL) in less severe asthma. No study has investigated the effect of BrEX on QOL neither on level of physical activity in severe asthma. A randomised controlled multicentre trial will include 190 adults with poor asthma control (Asthma Control Questionnaire (ACQ6)-score≥0.8) from seven outpatient departments and one specialized private clinic. Patients will be allocated to either usual care (no intervention) or breathing exercises (BrEX)-treatment consisting of 12-week intervention including three physiotherapist-sessions focusing on breathing pattern modification (Papworth Method; Buteyko technique) in rest and activity and 10 minutes home-exercise twice daily. Primary outcome is change in Mini Asthma Quality of Life Questionnaire (MiniAQLQ) at six-months follow-up.
Official title: BEAT DB-study; Breathing Exercises in Asthma Targeting Dysfunctional Breathing-a Randomised Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
193
Start Date
2017-04-27
Completion Date
2026-05-30
Last Updated
2026-06-09
Healthy Volunteers
No
Conditions
Interventions
Breathing Exercises
Key points in the intervention are * Reduction (or normalising) of the respiration rate; use of rhythmic, nasal inspiration, diaphragmatic breathing; reduction of depth of breath, longer expiration; breath-holding at functional residual capacity. * Relaxation, especially the neck, jaw, tongue, and shoulders. Emphasizing the impact of gravity to the body. * Inclusion of the breathing modification into walking and other physical activities. * Daily home exercise of BrEX.
Usual care
Participants will receive only short information given initially at recruitment. No instruction or booklet will be distributed in the Usual care-Group.
Locations (8)
Dep. of Physiotherapy and Dep. of Pulmonology
Silkeborg, Central Jutland, Denmark
Dep. of Physiotherapy and Dep. of Pulmonology
Bispebjerg, Danish Capital Region, Denmark
Allergi og Lungeklinikken Helsingør
Elsinore, Danish Capital Region, Denmark
Dep. of Physiotherapy and Dep. of Pulmonology
Hvidovre, Danish Capital Region, Denmark
Dep. of Physiotherapy and Dep. of Pulmonology
Aalborg, Region North, Denmark
Dep. of Physiotherapy and Dep. of Pulmonology
Næstved, Region Sjælland, Denmark
Dep. of Physiotherapy and Dep. of Pulmonology
Roskilde, Region Sjælland, Denmark
Dep. of Physiotherapy and Dep. of Pulmonology
Odense, Region Syddanmark, Denmark