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Biomechanical and Microstructural Properties of Ascending Aortic Aneurysms
Sponsor: Universitaire Ziekenhuizen KU Leuven
Summary
An aortic aneurysm (thoracic or abdominal) is a permanent dilatation of the aorta caused by weakening in the arterial wall. The feared complication is aortic rupture or dissection, leading to potentially lethal aortic bleeding and associated with mortality rates up to 95%. The current diagnosis criteria do not suffice, therefore the goal of this study is the development of an improved biomechanics-based and microstructural-based diagnostic tool.
Official title: BIOMECHANICAL AND MICROSTRUCTURAL PROPERTIES OF THE AORTIC WALL: A Pilot Study in Patients Undergoing Surgery for Ascending Aortic Aneurysms
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
180
Start Date
2017-01
Completion Date
2025-12
Last Updated
2024-07-01
Healthy Volunteers
No
Conditions
Interventions
Biomechanical and microstructural analysis of ATAA
Tissue collection; microstructural testing of tissue; mechanical testing of tissue .
ECG-gated CT
Image analysis of ECG-gated CT.
Locations (1)
UZ Leuven
Leuven, Vlaams Brabant, Belgium