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Propranolol Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery
Sponsor: Wake Forest University Health Sciences
Summary
This randomized pilot clinical trial studies how well propranolol hydrochloride works in treating patients with prostate cancer who are undergoing surgery. When stressed, the body makes a molecule that may prevent tumor cells from dying, and propranolol hydrochloride may affect the signals in cells that cause tumor cells survival and death.
Official title: Evaluating the Effect of ADRB2 Blockers on PKA/BAD/CREB Signaling in Patients Undergoing Prostatectomy
Key Details
Gender
MALE
Age Range
19 Years - Any
Study Type
INTERVENTIONAL
Enrollment
46
Start Date
2019-01-15
Completion Date
2023-02-28
Last Updated
2026-08-03
Healthy Volunteers
No
Conditions
Interventions
Laboratory Biomarker Analysis
Correlative studies
Propranolol Hydrochloride
Given PO
Questionnaire Administration
Ancillary studies
Survey Administration
Ancillary studies
Locations (1)
Comprehensive Cancer Center of Wake Forest University
Winston-Salem, North Carolina, United States