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Relation Between Pregnenolone Endocannabinoids in Normal-weight and Obese Men
Sponsor: University Hospital, Bordeaux
Summary
Measured plasmatic concentration of pregnenolone and endocannabinoid in fasting conditions and over a meal in obese and normal-weight men subjects, to research a dysfunction in the negative feed-back between pregnenolone and CB1 ligand in obese subjects. This dysfunction could participate to the hyperactivity of endocannabinoid system saw in obesity.
Key Details
Gender
MALE
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
25
Start Date
2017-05-30
Completion Date
2017-11-02
Last Updated
2026-05-22
Healthy Volunteers
No
Conditions
Interventions
Obese men
Biological measures before, just before, and after lunch, in obese men
Normal-weight men
Biological measures before, just before, and after lunch, in normal-weight men.
Locations (1)
Hôpital Haut-Lévêque
Pessac, France