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Chronic Hepatitis B Virus Infection in Zambia
Sponsor: University of Alabama at Birmingham
Summary
Chronic hepatitis B virus infection is a common condition in Zambia. Among Zambian blood donors, up to 8% are chronically infected with HBV. Despite the burden, awareness of HBV is low in Zambia and the Ministry of Health is in early stages of development of guidelines for HBV screening, treatment, and prevention. The purpose of this clinical cohort study is to characterize the clinical features of chronic HBV infection at UTH and describe treatment and care outcomes. The investigators will enroll 500 adults and follow the cohort for up to 5 years to assess short and long-term viral, serologic, and liver outcomes such as cirrhosis and liver cancer.
Official title: Chronic Hepatitis B Virus Infection in Zambia: a Prospective Clinical Cohort Study
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
OBSERVATIONAL
Enrollment
326
Start Date
2016-08-23
Completion Date
2026-06
Last Updated
2025-06-10
Healthy Volunteers
Not specified
Conditions
Interventions
Standard of care
Routine standard of care per Ministry of Health protocol, including blood draws and examinations.
Locations (1)
Tropical Gastroenterology and Nutrition Group
Lusaka, Zambia