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Medication Misuse and Dependence Among Elderly
Sponsor: University Hospital, Akershus
Summary
The project focuses on investigating problematic medication use, especially overuse of potentially addictive drugs among the elderly. The investigators aim firstly to develop and validate instruments for detecting and describing behavioral aspects and consequences of dependence on, and misuse of, prescription medication among elderly. In addition to evaluating diagnostic utility of screening instruments, the investigators aim to identify and report characteristics, risk factors and consequences of medication misuse and dependence among the elderly.
Official title: Medication Misuse and Dependence in Elderly Patients
Key Details
Gender
All
Age Range
65 Years - 90 Years
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2017-05-03
Completion Date
2024-12-31
Last Updated
2024-09-04
Healthy Volunteers
No
Interventions
Substance misuse screening
Diagnostic and Statistical manual of mental disorders, version 4 (DSM-IV)/MINI-international Neuropsychiatric interview (MINI interview) for Diagnostics of dependence, additional questions for DSM-V classification, severity of dependence scale (SDS)
EQ-5D
Health related Quality of life
Impulsivity screening
Barratts impulsivity test v. 11, Behavioural inhibition/behavioural activation test
Cognitive screening
Minimental state examination (MMSE), Hospital anxiety and depression scale (HADS), Trail-making test, clock drawing test
Functional tests
Timed up and go (TUG), Single leg balancing test (SLB)
Cognistat
Assessment of cognitive domains
Neuropsychological profiling
Controlled Oral Word Association Test, Categorical fluency tests, Wechsler Adult Intelligence Scale, Color-Word Interference Test (CWIT) from the Delis-Kaplan Executive Function test
Clinical interview
Interview for sociodemographics, utilisation of health care, economic varables, The De Jong Gierveld Loneliness Scale
Medication use
Detailed screen of used medications, interactions, side effects in electronic patient registry
Comorbidity
Charlson comorbidity index and Cumulated illness rating scale (CIRS) based on electronic patient registry
Locations (1)
Akershus University Hospital
Lørenskog, Norway