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Comparison of the Breast Tumor Microenvironment
Sponsor: Columbia University
Summary
The goal of the project is to identify a molecular signature of tumor stroma from "normal" adjacent breast tissue obtained prospectively at the time of breast conserving surgery before and after receiving intraoperative radiation therapy (IORT) in subjects that have luminal A and triple negative breast cancer. IORT is considered as being standard of care.
Official title: Differential Comparison of the Breast Tumor Microenvironment Between Luminal A and Triple Negative Breast Cancer With and Without Radiation Treatment
Key Details
Gender
FEMALE
Age Range
50 Years - Any
Study Type
OBSERVATIONAL
Enrollment
14
Start Date
2017-09-28
Completion Date
2027-12-01
Last Updated
2025-08-22
Healthy Volunteers
No
Interventions
Breast tissue collection
During Breast Conservation Surgery, one sample will be collected before and after IORT.
Blood sample collection
Blood will be collected before and after IORT, and at the two week follow-up.
Locations (1)
Columbia University Irving Medical Center
New York, New York, United States