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ENROLLING BY INVITATION
NCT03167203
PHASE1/PHASE2

A Safety Surveillance Study in Subjects With Macular Degenerative Disease Treated With Human Embryonic Stem Cell-derived Retinal Pigment Epithelial Cell Therapy

Sponsor: Astellas Institute for Regenerative Medicine

View on ClinicalTrials.gov

Summary

The purpose of this study is to is to evaluate the occurrence of late onset (i.e., greater than 5 years after treatment) adverse events of special interest (AESI) in participants who have received sub-retinal transplant of human embryonic stem cell derived - retinal pigment epithelial (hESC-RPE) cells in an AIRM-sponsored clinical trial. The events of special interest are adverse events (AEs) that are presumed to have a potential causal relationship to the hESC-RPE cells.

Official title: A Safety Surveillance Study of Events of Special Interest Occurring in Subjects With Macular Degenerative Disease Treated With Human Embryonic Stem Cell-derived Retinal Pigment Epithelial Cell Therapy

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

36

Start Date

2018-01-08

Completion Date

2029-03-31

Last Updated

2026-03-17

Healthy Volunteers

No

Interventions

BIOLOGICAL

Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells

Participants who have received sub-retinal transplant of hESC-RPE cells in an AIRM sponsored clinical trial

Locations (2)

Private Practice

Kansas City, Missouri, United States

Site GB44001

London, United Kingdom