Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT03193515

A Novel Multiplex ELISA Assay for Surveilling Patients With History of Bladder Cancer

Sponsor: Cedars-Sinai Medical Center

View on ClinicalTrials.gov

Summary

Voided urinary cytology (VUC) is the most widely used urine-based assay for detecting bladder cancer (BCa); however, it fails to detect approximately 50% of low-grade or early stage BCa when it is most curable. Furthermore, the detection rate of VUC for recurrent BCa is not much better. Because of this severe limitation, all patients who are under surveillance to monitor for recurrent BCa must undergo an invasive examination of the urinary bladder, where a miniature camera is inserted into the bladder and the bladder inspected (cystoscopy). We propose to improve the non-invasive detection of recurrent BCa by further validating a multiplex ELISA assay directed at a BCa-associated diagnostic signature in voided urine samples.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

300

Start Date

2016-12-30

Completion Date

2028-08

Last Updated

2026-02-04

Healthy Volunteers

No

Conditions

Locations (4)

Cedars-Sinai Medical Center

Los Angeles, California, United States

University of California San Francisco

San Francisco, California, United States

UT Southwestern Medical Center at Dallas

Dallas, Texas, United States

Kyoto University Graduate School of Medicine

Kyoto, Japan