Clinical Research Directory

Inclusion Criteria: * 18-60 years old * Able to provide informed consent * MOCA ≥26 * Fluent in English * Frequent nocturnal IEDs (≥ 10% of the sleep record) * Monitored on the adult epilepsy monitoring unit (EMU, for Aim 1 only) Additional inclusion criteria for Aim 3 * Frequent nocturnal seizures (≥1 per week) Exclusion Criteria: * Hearing impairment * Diagnosis of a sleep disorder (sleep apnea, periodic limb movements of sleep, or other medical conditions with frequent arousals) * Psychoactive medication use (other than AEDs, for example SSRIs, antipsychotics, BDZ, or stimulants) * Seizures ≤ 24 hours prior to study. * Alcohol or recreational drug use in the 24 hours prior to the study * BMI ≥ 30 * MOCA \<26 * History of recent travel across time zones within the 1 month prior to study activities * Shift work for 1 month prior to study activities Additional Exclusion Criteria for Aim 3 * No medication changes at least 1 month before study, and during 3 months of study activities