Clinical Research Directory
Browse clinical research sites, groups, and studies.
Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass
Sponsor: University of Colorado, Denver
Summary
Autologous blood transfused at the end of cardiopulmonary bypass will reduce total blood loss 24 hours after surgery and improve mitochondrial oxygen delivery measured by plasma succinate levels. The study design is a prospective randomized interventional trial of transfusion of fresh autologous whole blood versus standard of care expectant management of bleeding during elective cardiac surgery.
Official title: Targeted Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass: a Prospective Randomized Controlled Trial.
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2022-01-24
Completion Date
2026-09
Last Updated
2024-11-21
Healthy Volunteers
No
Conditions
Interventions
Fresh Autologous whole Blood
Subjects randomized this arm will receive fresh autologous whole blood
Standard of Care Expectant management of bleeding
the control group that will receive the standard of care expectant management of bleeding and transfusion of allogenic banked blood products
Locations (1)
University of Colorado Hospital
Aurora, Colorado, United States