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Early Detection and Treatment of Obstructive Sleep Apnoea in Infants With Down Syndrome
Sponsor: Institut Jerome Lejeune
Summary
Interventional, comparative, open-label, single-center study to demonstrate that early (from 6 months of age) and systematic (every 6 months) screening for Obstructive Sleep Apnoea (OSA) by polysomnography (PSG) in infants with Down syndrome during the first 3 years of life is associated with improved neurodevelopment at 3 years of age, with sustained benefits up to 5 years of age.
Key Details
Gender
All
Age Range
6 Months - 3 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2017-07-31
Completion Date
2024-02-29
Last Updated
2026-09-21
Healthy Volunteers
No
Interventions
Polysomnography (PSG)
PSG will be perfomed every 6 months in the Study group from the age of 6 months to 3 years
Locations (1)
Institut Jérome Lejeune
Paris, Sélectionnez l'État/Province, France