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Biomarkers of Synaptic Damage in Multiple Sclerosis
Sponsor: Neuromed IRCCS
Summary
A prospective and retrospective cohort study of about five years will be performed on blood and cerebrospinal fluid samples taken for diagnostic reasons from recruited patients within the Neuromed Neurology Unit. Subjects with other chronic neurodegenerative diseases such as Amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD) and Parkinson's disease (PD), and healthy subjects subjected to blood sampling and / or lumbar puncture for clinical reasons will be recruited As control groups.
Official title: Identification of New Biomarkers Useful to Define the Course of Multiple Sclerosis and Study of the Mechanisms That Promote Synaptic Damage
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2017-11-22
Completion Date
2027-09-30
Last Updated
2022-10-28
Healthy Volunteers
No
Interventions
lumbar puncture
lumbar puncture performed to detect OCB for diagnostic purposes
Locations (1)
IRCCS Neuromed
Pozzilli, Isernia, Italy