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RECRUITING
NCT03218137
PHASE4

Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions

Sponsor: Weill Medical College of Cornell University

View on ClinicalTrials.gov

Summary

Unblinded, controlled, non-randomized, mechanistic study to determine whether physiological mechanisms underlying PVC are sensitive to adenosine. One hundred subjects undergoing clinically-indicated, standard-of-care cardiac electrophysiology study (EPS) procedure for PVCs will receive adenosine and/or verapamil to learn if their arrhythmias are inducible similarly to sustained ventricular tachycardia.

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2017-02-13

Completion Date

2025-12-31

Last Updated

2025-08-03

Healthy Volunteers

Yes

Interventions

DRUG

Adenosine

Adenosine: 0.84 mg/kg (140 mcg/kg/minute IV for 6 minutes) Verapamil 0.15 mg/kg

Locations (1)

Weill Cornell Medicine

New York, New York, United States