Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Trial Testing Early vs Late Onset of EPO Alfa Treatment in Lower Risk MDS
Sponsor: Groupe Francophone des Myelodysplasies
Summary
This is an open-label, randomized, multicenter, phase III study Patients with baseline Hb comprised between 9 and 10.5g/dl will be randomized to receive EPO Alfa 60000 UI/week for at least 12 weeks: * Either at diagnosis Or * at the Hb threshold chosen for RBC transfusions (must be \< 9g/dl)
Official title: A Randomized Trial Testing Early vs Late Onset of EPO Alfa Treatment in Lower Risk MDS With Non RBC Transfusion Dependent Anemia and Without Del 5q
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
124
Start Date
2018-03-26
Completion Date
2028-10-01
Last Updated
2025-03-11
Healthy Volunteers
No
Conditions
Interventions
EPREX
60 000 U/week for at least 12 weeks
Locations (39)
Chu Amiens
Amiens, France
CH Angers
Angers, France
CH Avignon
Avignon, France
Centre Hospitalier de La Cote Basque
Bayonne, France
Hopital Nord Franche-Comté
Belfort, France
CHU de Besançon
Besançon, France
Hopital Avicenne
Bobigny, France
Hôpital Morvan
Brest, France
CHU de Caen
Caen, France
CH de Sevigné
Cesson, France
CH de Cholet
Cholet, France
CHU Estaing
Clermont-Ferrand, France
CHSF Gilles de Corbeil
Corbeil-Essonnes, France
Hôpital Henri-Mondor
Créteil, France
CHU de Grenoble
Grenoble, France
Centre Hospitalier du Mans
Le Mans, France
Clinique Victor Hugo
Le Mans, France
Hopital Saint-Vincent de Paul
Lille, France
CHRU Limoges
Limoges, France
Centre Hospitalier Lyon Sud
Lyon, France
IPC
Marseille, France
Centre Hospitalier du Mont de Marsan
Mont-de-Marsan, France
CHU de Nantes
Nantes, France
CHU de Nice
Nice, France
Hopital St Louis T4
Paris, France
Centre Hospitalier Joffre-Perpignan
Perpignan, France
Sophie Dimicoli-Salazar
Pessac, France
CH de Périgueux
Périgueux, France
CHU de Poitiers
Poitiers, France
CHR d'Annecy
Pringy, France
CHRU de Reims
Reims, France
CHU Pontchaillou
Rennes, France
Centre Henri Becquerel
Rouen, France
CH Saint Nazaire
Saint-Nazaire, France
Centre Hospitalier Universitaire de STRASBOURG
Strasbourg, France
IUCT Oncopole
Toulouse, France
CH de Troyes
Troyes, France
CH Valence
Valence, France
CHU Brabois
Vandœuvre-lès-Nancy, France