Clinical Research Directory

Inclusion Criteria: 1. Subject must be at least 30 years of age. 2. Subject is able to verbally confirm understandings of risks, benefits and treatment alternatives of receiving the Vitamin C+E or Statin or Dual, and he/she or his/her legally authorized representative provides written informed consent prior to any study related procedure. 3. Subject must have symptoms that are consistent with vasospastic angina with planned Coronary angiography and Provocation test. Exclusion Criteria: 1. Patient who has organic coronary stenosis in main coronary branch at least 50% luminal narrowing after intracoronary nitroglycerin injection 2. Patient who has continuously taken Vitamin C or Vitamin E or Statin within 3months before Admission 3. Creatinine level ≥ 2.0mg/dL or dependence on dialysis. 4. Severe hepatic dysfunction (AST and ALT: 3 times upper normal reference values). 5. Active Myopathy or elevated Creatine kinase enzyme level (3 times upper normal reference values). 6. History of Severe hepatic dysfunction or Rhabdomyolysis due to statin side effect 7. Female of childbearing potential, unless a recent pregnancy test is negative, who possibly plan to become pregnant any time after enrollment into this study. 8. History of Urolithiasis 9. Non-cardiac co-morbid conditions are present with life expectancy \<1 year or that may result in protocol non-compliance (per site investigator's medical judgment).