Clinical Research Directory

Inclusion Criteria: * Subject is capable of understanding and complying with the protocol * Good physical and mental health (normal physical exam, ECG, blood and urine chemistries, including absences of history or laboratory evidence of diabetes) * Body Mass Index between 18-30, inclusive * Age 21-50 years (age will be verified by driver's license or other valid form of identification) * Have used alcohol, on average, between 5-15 drinks per week over the past 6 months. * Have a stable living situation with current postal address Exclusion Criteria: * Meets criteria for current alcohol or substance use disorders (Past alcohol or substance use disorders greater than 3 years ago is acceptable) * Concurrent diagnosis of Axis I disorder * bMaintained on an antipsychotic or antidepressant medication; taking prescription medications except certain short-term anti-fungal agents and some tropical creams for dermal conditions * Heavy alcohol drinkers (greater than 15 drinks per week) * Tobacco use greater than 5 cigarettes per day * History of major head trauma resulting in cognitive impairment or history of seizure disorder * Heavy caffeine use (greater than 500 mg on a regular daily basis) * Subject has active hepatitis and/or aspartate aminotransferase (AST), alanine aminotransferase (ALT) \> 3x the upper limit of normal * For female volunteers, a positive pregnancy test