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Surveillance of Patients With Precancerous Lesions of the Stomach
Sponsor: University of Latvia
Summary
The project will aim to identify and determine subgroups of patients with different risks of progression to gastric cancer and to assess appropriate follow-up intervals. Implementing risk stratification only high risk individuals will be offered and performed endoscopic surveillance.
Official title: Surveillance Strategies of Patients With Precancerous Conditions and Lesions in the Stomach
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
2000
Start Date
2017-06-19
Completion Date
2027-12
Last Updated
2018-08-21
Healthy Volunteers
Yes
Interventions
Upper endoscopy with biopsies
Upper endoscopy with proper biopsy work-up will be used for identification and stratification of gastric lesions as well as acquisition of biopsies for histopathological examination, including H.pylori detection
Plasma/serum sampling
Plasma/serum sampling will be used to obtain information for group stratification, e.g. H.pylori status determination, serum biomarkers
Biopsies for gastric microbiota
During upper endoscopy biopsies for gastric microbiota analysis will be obtained
Faecal sample acquisition
Faecal samples will be obtained for faecal occult blood testing as well as microbiota analysis
Locations (1)
University of Latvia
Riga, Latvia