Clinical Research Directory

Inclusion Criteria: * Patients suitable for adjuvant radiotherapy for cancer of the breast (invasive or in situ) including breast patients receiving neo-adjuvant chemotherapy. Patients receiving chemotherapy should have completed their course of chemotherapy (anthracyclines) at least one month prior to radiotherapy commencing. * No other malignancy prior to treatment for the specified tumour types except basal cell or squamous cell carcinoma of the skin * No evidence of distant metastases * Patients able to provide a venous blood sample * Willingness and ability to comply with scheduled visits, treatment plans and available for follow up * Greater than 18 years of age; no upper age limit * The capacity to understand the patient information sheet and the ability to provide written informed consent * Patients must be affiliated to a Social Security System Exclusion Criteria: * Patients with metastatic disease * Prior irradiation at the same site * Planned use of protons * Breast patients receiving concomitant chemo-radiation * Male breast cancer patients * Mastectomy patients * Bilateral breast cancer * Mental disability or patient otherwise unable to give informed consent * Limited life expectancy due to co-morbidity * Pregnant patients * Partial breast irradiation * Patients with breast implants if not removed during surgery