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Randomized Study of Elective Regional Lymph Node Irradiation in N1 Breast Cancer
Sponsor: Samsung Medical Center
Summary
This study evaluates the impact of elective regional lymph node irradiation on N1 breast cancer patients receiving post-lumpectomy radiotherapy and anthracycline plus taxane (AT)-based chemotherapy. We randomly assign patients having one to three metastatic lymph nodes (pN1) after breast-conserving surgery (BCS) and AT-based chemotherapy to undergo either whole-breast and regional nodal irradiation (WB+RNI group) or whole-breast irradiation alone (WBI group).
Official title: A Phase III Prospective Randomized Study of Elective Regional Lymph Node Irradiation in Pathologic N1 Breast Cancer Patients Treated With Breast Conserving Surgery
Key Details
Gender
FEMALE
Age Range
20 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
827
Start Date
2017-04-01
Completion Date
2029-12-30
Last Updated
2023-11-27
Healthy Volunteers
No
Conditions
Interventions
Whole breast irradiation
Radiotherapy to the whole breast alone.
Whole breast and nodal irradiation
Radiotherapy to the whole breast and regional lymph nodes.
Locations (1)
Samsung Medical Center
Seoul, South Korea