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Pulmonary Arterial Hypertension Improvement With Nutrition and Exercise (PHINE)
Sponsor: The Cleveland Clinic
Summary
The purpose of this study is to investigate the extent to which diet and exercise may improve PAH through the modulation of insulin sensitivity. The central hypothesis is that dysregulated glucose metabolism elicits a response in PAH patients that can be modified by exercise and diet, thereby leading to improvements in pulmonary vascular disease.
Official title: Pulmonary Arterial Hypertension Improvement With Nutrition and Exercise (PHINE) A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
34
Start Date
2017-09-27
Completion Date
2026-06-30
Last Updated
2025-09-24
Healthy Volunteers
No
Interventions
Nutrition and Exercise
5 times a week exercise training and biweekly diet counseling for 12 weeks.
Locations (1)
Cleveland Clinic Foundation
Cleveland, Ohio, United States