Clinical Research Directory

Inclusion Criteria: * Maternal age ≥ 18 years and \<50 years. * Diagnosis of gestational hypertension\* or preeclampsia\^ at any time during pregnancy, labor or postpartum. * defined as isolated systolic BP of 140 mm Hg or greater, a diastolic BP of 90 mm Hg or greater, or both) or \^ defines as new-onset hypertension plus new-onset proteinuria, or in the absence of proteinuria, preeclampsia is diagnosed as hypertension in association with thrombocytopenia (platelet count less than 100,000/microliter), impaired liver function (elevated blood levels of liver transaminases to twice the normal concentration), the new development of renal insufficiency (elevated serum creatinine greater than 1.1 mg/dL or a doubling of serum creatinine in the absence of other renal disease), pulmonary edema, or new-onset cerebral or visual disturbances.) Exclusion Criteria: * Subject requiring antihypertensive therapy at time of screening. * Planned discharge with oral anti-hypertensive medication. * Contraindication to hydrochlorothiazide (advanced renal failure or anuria, hypersensitivity to sulfonamides). * Subject not able to follow up postpartum. * Lactose intolerance. * Pre-gestational diabetes.