Clinical Research Directory
Browse clinical research sites, groups, and studies.
PREDICT Cytomegalovirus (CMV)
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Summary
The overall objective of this study is to establish a personalized test to measure individualized cytomegalovirus (CMV) specific immunity in lung transplant recipients in an effort to guide antiviral prophylaxis duration in clinical practice. Targeted participants are those: * enrolled in clinical research study CTOT-20 (Clinical Trials.gov ID: NCT02631720) who * are CMV recipient positive by serology as determined using methods in accordance with current local organ procurement organization policies.
Official title: Prospective Multicenter Cytomegalovirus (CMV) Specific Immune Monitoring to Predict Patient Risk After Lung Transplantation (CTOT-22)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
84
Start Date
2017-10-31
Completion Date
2019-11-25
Last Updated
2026-09-25
Healthy Volunteers
No
Conditions
Interventions
Procedure
Serial blood draws. Participants will be enrolled either pre-transplant or within 45 days post-transplant and will be followed over the course of 18 months post transplant. Protocol mandated serial measurement of cytomegalovirus (CMV)-specific immune signature will occur pre-transplant (as applicable) and at post-transplant timepoint months 2, -3, -6, -9, -12 and -18.
Locations (4)
Johns Hopkins Hospital: Transplantation
Baltimore, Maryland, United States
Duke University Medical Center: Transplantation
Durham, North Carolina, United States
Cleveland Clinic Foundation: Transplantation
Cleveland, Ohio, United States
Toronto General Hospital: Transplantation
Toronto, Canada