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Concordance of Imaging and Pathology Diagnosis of Extranodal Tumour Deposits
Sponsor: Imperial College London
Summary
Any patient with a suspected primary adenocarcinoma of the colon, sigmoid or rectum undergoing surgery are eligible. The date of surgery must be known prior to registration. This trial aims to determine if image mapping techniques can improve the concordance between imaging and pathology detection of tumour deposits. Lymph nodes and tumour deposits will be identified on pre-operative scans and mapped by radiologists then shared with pathologists prior to processing the resected specimen. Patients will be managed at their local hospital with standard follow-up. Patients will be followed up for 5 years.
Key Details
Gender
All
Age Range
16 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2017-10-16
Completion Date
2031-12
Last Updated
2024-10-17
Healthy Volunteers
No
Conditions
Interventions
MRI mapping to guide pathological sampling of extranodal tumour deposits
Radiologist to mark areas where extranodal disease is identified on MRI. The pathologist will use this to take additional samples for analysis. This will allow better pathological staging and will affect treatment decisions for patients.
Locations (1)
Royal Marsden Hospital NHS Foundation Trust
London, Surrey, United Kingdom