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Treatment of Supine Hypertension in Autonomic Failure (CPAP)
Sponsor: Vanderbilt University Medical Center
Summary
Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of this study is to assess whether continuous positive airway pressure (CPAP) decreases blood pressure in autonomic failure patients with supine hypertension.
Official title: Treatment of Supine Hypertension in Autonomic Failure With Continuous Positive Airway Pressure
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2017-09-21
Completion Date
2026-12-21
Last Updated
2025-11-06
Healthy Volunteers
No
Conditions
Interventions
continuous positive airway pressure (CPAP)
Continuous positive airway pressure(CPAP) will be applied during the night starting from 20:00. CPAP level will be determined during an acute CPAP trial.
Placebo
Placebo pill or patch. Single dose
Locations (1)
Autonomic Dysfunction Center/ Vanderbilt University Medical Center
Nashville, Tennessee, United States