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Sentinel Node Mapping in High Risk Endometrial Cancer
Sponsor: AC Camargo Cancer Center
Summary
This study will evaluate the role of systematic lymphadenectomy after sentinel node (SLN) mapping in high risk endometrial cancer (high grade histologies or deep myometrial invasion). The participants will be randomized in a non-inferiority controlled trial in 2 groups: SLN mapping or SLN mapping followed by systematic lymphadenectomy.
Official title: Sentinel Node Mapping Versus Sentinel Node Mapping With Systematic Lymphadenectomy in High Risk Endometrial Cancer: a Open Label, Non-inferiority, Randomized Trial.
Key Details
Gender
FEMALE
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
178
Start Date
2017-12-22
Completion Date
2024-12-20
Last Updated
2024-07-30
Healthy Volunteers
No
Conditions
Interventions
Sentinel Node Mapping
At least one sentinel node should be retrieved in both hemipelvis. If no sentinel node is found in one hemipelvis, a side specific lymphadenectomy will be performed.
Lymphadenectomy
Systematic Pelvic and Para-Aortic Lymphadenectomy
Locations (5)
Hospital Erasto Gaertner
Curitiba, Paraná, Brazil
Hospital do Cancer de Barretos
Barretos, São Paulo, Brazil
AC Camargo Cancer Center
São Paulo, São Paulo, Brazil
Albert Einstein Hospital
São Paulo, São Paulo, Brazil
Sao Camilo Oncologia
São Paulo, São Paulo, Brazil