Clinical Research Directory

Inclusion Criteria: * Patients undergoing Roux-en-Y gastric bypass surgery; * Patients who able to tolerate general anesthetic and pneumoperitoneum; * Patients who able to provide informed consent for the surgery; * Patients over the age of 18 years; Exclusion Criteria: * Patient undergoing planned sleeve gastrectomy (intra-op conversion to sleeve gastrectomy after delivery of Ropivacaine/placebo will be included and analyzed using intention-to-treat approach) * Patients with an allergy to local anesthetics * Patients with severe underlying cardiovascular disease (ie: congestive heart failure, conduction abnormalities, and ischemic heart disease) * Patients with chronic renal disease Stage 3 or greater (Creatinine clearance less than 60mL/min) * Patients with hepatic dysfunction Child-Pugh Class B or C * Patients with previous foregut surgery including esophageal, gastric, liver, and pancreas resections * Patients weighing less than or equal to 100 kilograms as measured in the pre-admission unit * Patients enrolled in any other study involving involve tissue biopsy. * Patients with Chronic Pain and Chronic Opioid use- Oral Morphine Equivalent of \>100mg/day