Clinical Research Directory

Inclusion Criteria: * Male or female subjects 18-70 years of age. * Subject has a confirmed diagnosis of acute type A aortic dissection with subtype A2. * Subject is willing and able to give written consent for the trial. If the subject is unconscious or under the influence of medications which render him or her unable to give fully informed consent, a guardian may provide informed consent for the subject regarding trial participation. Exclusion Criteria: * Subjects with known allergy to albumin, bovine products, or glutaraldehyde. * Subjects who have been treated with an investigational product who have not completed the entire follow-up period. * Subjects who do not meet the eligibility criteria, including those who do not wish to participate or give informed consent for trial participation, will not be enrolled into the trial, and will be offered equivalent, non-trial surgical or other treatment, as judged appropriate by the investigator. * Subjects with previous cardiac and aortic surgery. * End stage malperfusion syndromes (i.e. end-organ failure such as coma, paraplegia, hemiplegia, intestinal necrosis, or hepatic failure). * Subjects with Marfan syndrome or other connective tissue disorders. * Previous chronic dissections resulting from non-cardiac surgery and/or trauma. * Concomitant surgery of valve replacement (both in screening and intraoperative).