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RECRUITING
NCT03384108
NA

In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells

Sponsor: Mayo Clinic

View on ClinicalTrials.gov

Summary

This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects while comparing it to an ex vivo approach

Official title: In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells in Healthy Subjects Using Stable Isotope Resolved Metabolomics: A Pilot Study

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2017-09-01

Completion Date

2028-01

Last Updated

2026-02-25

Healthy Volunteers

Yes

Conditions

Interventions

OTHER

5-13C-Glutamine

Intravenous infusion of 5-13C-Glutamine

OTHER

Bone marrow aspiration

Bone marrow aspiration of bone marrow aspirate

Locations (1)

Mayo Clinic

Rochester, Minnesota, United States