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Role of the Posterior Parietal Cortex in the Processing of Sensory Information
Sponsor: University Hospital, Lille
Summary
Although the primary motor cortex is considered has the common final pathway of motor commands, it is influenced by several structures as, for example, the premotor cortex and the posterior parietal cortex which are involved in motor planning and programming and which integrates movement-induced sensory impute (parieto-frontal circuits). Several studies have shown that there are some direct functional connections between the premotor cortex and the posterior parietal cortex and from these two regions to the primary motor cortex. The posterior parietal cortex can then be considered as a sensorimotor interface whose function in planification and motor control of upper limb is well demonstrated. The hypothesis is that the posterior parietal cortex could participate to the modulation of motor cortex excitability by proprioceptive sensory inputs namely long latency afferent inhibition and afferent induced facilitation.
Official title: Role of the Posterior Parietal Cortex in the Processing of Sensory Information Modulating the Excitability of the Primary Motor Cortex in Humans
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2016-01-08
Completion Date
2021-07-18
Last Updated
2026-04-22
Healthy Volunteers
Yes
Conditions
Interventions
Transcranial Magnetic Stimulation (TMS)
Transitory inactivation of the posterior parietal cortex and measure of sensorimotor integration.
Electrical Muscle Activity (EMG)
Electrodes for the collection of EMG activity will be glued on the skin next to the first interosseus dorsalis muscle, the Abductor digiti minimi, the Extensor carpi radialis and the Abductor pollicis brevis. EMG signals will be stored on computer for off-line analysis using Signal © software (Cambridge Electronic Design, Cambridge, UK)
Locations (1)
Hôpital Roger Salengro, CHRU de Lille
Lille, France