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TERMINATED
NCT03386188
NA

Role of the Posterior Parietal Cortex in the Processing of Sensory Information

Sponsor: University Hospital, Lille

View on ClinicalTrials.gov

Summary

Although the primary motor cortex is considered has the common final pathway of motor commands, it is influenced by several structures as, for example, the premotor cortex and the posterior parietal cortex which are involved in motor planning and programming and which integrates movement-induced sensory impute (parieto-frontal circuits). Several studies have shown that there are some direct functional connections between the premotor cortex and the posterior parietal cortex and from these two regions to the primary motor cortex. The posterior parietal cortex can then be considered as a sensorimotor interface whose function in planification and motor control of upper limb is well demonstrated. The hypothesis is that the posterior parietal cortex could participate to the modulation of motor cortex excitability by proprioceptive sensory inputs namely long latency afferent inhibition and afferent induced facilitation.

Official title: Role of the Posterior Parietal Cortex in the Processing of Sensory Information Modulating the Excitability of the Primary Motor Cortex in Humans

Key Details

Gender

All

Age Range

18 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2016-01-08

Completion Date

2021-07-18

Last Updated

2026-04-22

Healthy Volunteers

Yes

Conditions

Interventions

DEVICE

Transcranial Magnetic Stimulation (TMS)

Transitory inactivation of the posterior parietal cortex and measure of sensorimotor integration.

DEVICE

Electrical Muscle Activity (EMG)

Electrodes for the collection of EMG activity will be glued on the skin next to the first interosseus dorsalis muscle, the Abductor digiti minimi, the Extensor carpi radialis and the Abductor pollicis brevis. EMG signals will be stored on computer for off-line analysis using Signal © software (Cambridge Electronic Design, Cambridge, UK)

Locations (1)

Hôpital Roger Salengro, CHRU de Lille

Lille, France