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RECRUITING
NCT03386981

Metabolic Profile of Bone in Professional Athletes

Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio

View on ClinicalTrials.gov

Summary

Physical activity is a key stimulus for bone metabolism through both direct mechanisms (e.g., as a result of the applied load and/or impact) and indirect mechanisms (e.g., the activation of several metabolic pathways and the production of several mediators and effectors that have systemic effects). However, different kinds of physical activity exert different effects on bone and endocrine system. Aim of the study is to investigate the effects of different kinds of physical activity on bone metabolism and on the relationships existing between bone metabolism, energy metabolism, hormone profile, and organ functionality.

Official title: Study of the Metabolic Profile of Bone in Professional Athletes as a Function of the Kind of Physical Activity Performed

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2016-02-04

Completion Date

2027-02-04

Last Updated

2025-09-11

Healthy Volunteers

Yes

Interventions

OTHER

blood and saliva tests

Blood and saliva will be tested for: bone turnover markers, cytokines, chemokines, adipokines, myokines and hormones regulating bone and energy metabolism

Locations (1)

Istituto Ortopedico Galeazzi

Milan, Italy