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Metabolic Profile of Bone in Professional Athletes
Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Summary
Physical activity is a key stimulus for bone metabolism through both direct mechanisms (e.g., as a result of the applied load and/or impact) and indirect mechanisms (e.g., the activation of several metabolic pathways and the production of several mediators and effectors that have systemic effects). However, different kinds of physical activity exert different effects on bone and endocrine system. Aim of the study is to investigate the effects of different kinds of physical activity on bone metabolism and on the relationships existing between bone metabolism, energy metabolism, hormone profile, and organ functionality.
Official title: Study of the Metabolic Profile of Bone in Professional Athletes as a Function of the Kind of Physical Activity Performed
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2016-02-04
Completion Date
2027-02-04
Last Updated
2025-09-11
Healthy Volunteers
Yes
Conditions
Interventions
blood and saliva tests
Blood and saliva will be tested for: bone turnover markers, cytokines, chemokines, adipokines, myokines and hormones regulating bone and energy metabolism
Locations (1)
Istituto Ortopedico Galeazzi
Milan, Italy