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Medial Unicondylar Knee Arthroplasty vs Total Knee Arthroplasty
Sponsor: University Hospital, Gentofte, Copenhagen
Summary
In treatment of isolated medial unicondylar osteoarthritis of the knee (MU-OA), it is possible to choose between surgery with a unicondylar knee arthroplasty (UKA), or a total knee arthroplasty (TKA). Supporters of TKA suggest that this treatment gives a more predictable and better result, whereas supporters of UKA suggest that it is unnecessary to remove decent and functional cartilage in other compartments, and also that generally the UKA gives better results under certain circumstances. If the UKA is worn out or loosens, revision surgery will be relatively easy, whereas revision-surgery after a TKA can be much more problematic. Also, it is of great interest to measure the direct costs of these treatments. Both general hospital costs, but also costs in societal in terms of sick-days, pain-killer expenditure, and physiotherapy. The aim of this study is to compare the results, in terms of 1) patient-reported outcomes, 2) clinical results including prosthetic survival and 3) costs.
Official title: Randomized Clinical Trial of Medial Unicompartmentel Versus Total Arthroplasty for Medial Tibio-femoral OA.
Key Details
Gender
All
Age Range
18 Years - 110 Years
Study Type
INTERVENTIONAL
Enrollment
350
Start Date
2017-08-17
Completion Date
2041-10-16
Last Updated
2023-10-23
Healthy Volunteers
Yes
Conditions
Interventions
Unicondylar Knee Arthroplasty
Incision will be midline incision, as with a TKA, for maximum security of blinding. Standard operative technique will hereafter be used, with minor individual preferences for each surgeon as to whether tourniquet/not, drain or not.
Total Knee Arthroplasty
Incision will be midline incision, as standard. Standard operative technique will hereafter be used, with minor individual preferences for each surgeon as to whether tourniquet/not, drain or not.
Locations (11)
Bispebjerg Hospital
Copenhagen, Bispebjerg, Denmark
Randers Hospital
Randers, Central Jutland, Denmark
Silkeborg Hospital
Silkeborg, Central Jutland, Denmark
Gentofe Hospital
Copenhagen, Gentofte, Denmark
Aarhus Universitetshospital
Aarhus, Denmark
Aalborg Universitetshospital, Farsø
Farsø, Denmark
Andreas Kappel
Farsø, Denmark
Frederikshavn Sygehus
Frederikshavn, Denmark
Næstved Sygehus
Næstved, Denmark
Svendborg Sygehus
Svendborg, Denmark
Vejle Sygehus
Vejle, Denmark