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ACTIVE NOT RECRUITING
NCT03396640
NA

Medial Unicondylar Knee Arthroplasty vs Total Knee Arthroplasty

Sponsor: University Hospital, Gentofte, Copenhagen

View on ClinicalTrials.gov

Summary

In treatment of isolated medial unicondylar osteoarthritis of the knee (MU-OA), it is possible to choose between surgery with a unicondylar knee arthroplasty (UKA), or a total knee arthroplasty (TKA). Supporters of TKA suggest that this treatment gives a more predictable and better result, whereas supporters of UKA suggest that it is unnecessary to remove decent and functional cartilage in other compartments, and also that generally the UKA gives better results under certain circumstances. If the UKA is worn out or loosens, revision surgery will be relatively easy, whereas revision-surgery after a TKA can be much more problematic. Also, it is of great interest to measure the direct costs of these treatments. Both general hospital costs, but also costs in societal in terms of sick-days, pain-killer expenditure, and physiotherapy. The aim of this study is to compare the results, in terms of 1) patient-reported outcomes, 2) clinical results including prosthetic survival and 3) costs.

Official title: Randomized Clinical Trial of Medial Unicompartmentel Versus Total Arthroplasty for Medial Tibio-femoral OA.

Key Details

Gender

All

Age Range

18 Years - 110 Years

Study Type

INTERVENTIONAL

Enrollment

350

Start Date

2017-08-17

Completion Date

2041-10-16

Last Updated

2023-10-23

Healthy Volunteers

Yes

Interventions

PROCEDURE

Unicondylar Knee Arthroplasty

Incision will be midline incision, as with a TKA, for maximum security of blinding. Standard operative technique will hereafter be used, with minor individual preferences for each surgeon as to whether tourniquet/not, drain or not.

PROCEDURE

Total Knee Arthroplasty

Incision will be midline incision, as standard. Standard operative technique will hereafter be used, with minor individual preferences for each surgeon as to whether tourniquet/not, drain or not.

Locations (11)

Bispebjerg Hospital

Copenhagen, Bispebjerg, Denmark

Randers Hospital

Randers, Central Jutland, Denmark

Silkeborg Hospital

Silkeborg, Central Jutland, Denmark

Gentofe Hospital

Copenhagen, Gentofte, Denmark

Aarhus Universitetshospital

Aarhus, Denmark

Aalborg Universitetshospital, Farsø

Farsø, Denmark

Andreas Kappel

Farsø, Denmark

Frederikshavn Sygehus

Frederikshavn, Denmark

Næstved Sygehus

Næstved, Denmark

Svendborg Sygehus

Svendborg, Denmark

Vejle Sygehus

Vejle, Denmark