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Microbiota Transfer Therapy for Adults With Autism Spectrum Disorder (ASD) Who Have Gastrointestinal Disorders
Sponsor: Arizona State University
Summary
This is a clinical trial of Microbiota Transplant Therapy (MTT) for adults with autism spectrum disorders (ASD) who have gastrointestinal problems. Previous research has shown that individuals with ASD have a low diversity of gut bacteria, and low diversity is generally associated with poor gastrointestinal (GI) health. We previously found that MTT therapy for children with ASD and GI symptoms was helpful in reducing their GI symptoms, reducing their ASD symptoms, and increasing their diversity of gut bacteria. This clinical trial will investigate the hypothesis that MTT therapy will be helpful for adults with ASD who have GI symptoms.
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
55
Start Date
2018-01-04
Completion Date
2024-12-15
Last Updated
2023-01-09
Healthy Volunteers
No
Interventions
Vancomycin
Oral vancomycin is administered to reduce pathogenic bacteria.
MoviPrep
MoviPrep is given at the end of vancomycin therapy to remove the vancomycin and remaining bacteria prior to administering Full-Spectrum Microbiota
Full Spectrum Microbiota
Gut bacteria from healthy human donors are administered orally in a pill form
Locations (1)
Arizona State University
Tempe, Arizona, United States