Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Sponsor: UCB Biopharma SRL
Summary
This is a study to compare the efficacy of bimekizumab versus adalimumab in the treatment of subjects with moderate to severe chronic plaque psoriasis (PSO).
Official title: A Phase 3, Multicenter, Randomized, Double-Blind Study With an Active-Controlled Initial Treatment Period Followed by a Dose-Blind Maintenance Treatment Period to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
478
Start Date
2018-01-26
Completion Date
2020-02-26
Last Updated
2026-04-15
Healthy Volunteers
No
Interventions
Bimekizumab
Subjects will receive bimekizumab at pre-defined timepoints in dose regimen 1 and/or dose regimen 2.
Adalimumab
Adalimumab will be administered according to the labeling recommendations.
Placebo
Subjects will receive Placebo at pre-specified time points to maintain the blinding of the Investigational Medicinal Products (IMP).
Locations (77)
Ps0008 957
Glendale, Arizona, United States
Ps0008 927
Los Angeles, California, United States
Ps0008 955
San Diego, California, United States
Ps0008 943
San Luis Obispo, California, United States
Ps0008 967
Santa Monica, California, United States
Ps0008 939
Danbury, Connecticut, United States
Ps0008 934
Washington D.C., District of Columbia, United States
Ps0008 906
Boca Raton, Florida, United States
Ps0008 936
Tampa, Florida, United States
Ps0008 900
West Des Moines, Iowa, United States
Ps0008 905
Overland Park, Kansas, United States
Ps0008 940
Beverly, Massachusetts, United States
Ps0008 925
Brighton, Massachusetts, United States
Ps0008 917
Troy, Michigan, United States
Ps0008 908
East Windsor, New Jersey, United States
Ps0008 961
Rocky Mount, North Carolina, United States
Ps0008 935
Winston-Salem, North Carolina, United States
Ps0008 932
Oklahoma City, Oklahoma, United States
Ps0008 929
Portland, Oregon, United States
Ps0008 945
Greer, South Carolina, United States
Ps0008 931
Dallas, Texas, United States
Ps0008 924
Houston, Texas, United States
Ps0008 951
Houston, Texas, United States
Ps0008 008
East Melbourne, Australia
Ps0008 004
Fremantle, Australia
Ps0008 007
Hectorville, Australia
Ps0008 010
Kogarah, Australia
Ps0008 005
Phillip, Australia
Ps0008 009
Woolloongabba, Australia
Ps0008 659
Calgary, Canada
Ps0008 663
Mississauga, Canada
Ps0008 660
Montreal, Canada
Ps0008 661
Peterborough, Canada
Ps0008 662
Toronto, Canada
Ps0008 664
Toronto, Canada
Ps0008 657
Waterloo, Canada
Ps0008 669
Windsor, Canada
Ps0008 670
Windsor, Canada
Ps0008 674
Winnipeg, Canada
Ps0008 207
Berlin, Germany
Ps0008 218
Bonn, Germany
Ps0008 203
Dresden, Germany
Ps0008 211
Hamburg, Germany
Ps0008 220
Hamburg, Germany
Ps0008 215
Lübeck, Germany
Ps0008 213
Mahlow, Germany
Ps0008 205
Osnabrück, Germany
Ps0008 217
Schweinfurt, Germany
Ps0008 252
Budapest, Hungary
Ps0008 254
Budapest, Hungary
Ps0008 255
Budapest, Hungary
Ps0008 256
Debrecen, Hungary
Ps0008 251
Gyula, Hungary
Ps0008 260
Szeged, Hungary
Ps0008 355
Bialystok, Poland
Ps0008 362
Bialystok, Poland
Ps0008 371
Bydgoszcz, Poland
Ps0008 352
Gdansk, Poland
Ps0008 359
Katowice, Poland
Ps0008 366
Katowice, Poland
Ps0008 363
Krakow, Poland
Ps0008 360
Lodz, Poland
Ps0008 372
Lodz, Poland
Ps0008 356
Lublin, Poland
Ps0008 364
Nowa Sól, Poland
Ps0008 353
Szczecin, Poland
Ps0008 354
Warsaw, Poland
Ps0008 365
Wroclaw, Poland
Ps0008 367
Wroclaw, Poland
Ps0008 373
Wroclaw, Poland
Ps0008 405
Saint Petersburg, Russia
Ps0008 401
Saratov, Russia
Ps0008 406
Yaroslavl, Russia
Ps0008 702
Gwangju, South Korea
Ps0008 700
Seoul, South Korea
Ps0008 754
Taipei, Taiwan
Ps0008 755
Taipei, Taiwan