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Hydrops: Diagnosing & Redefining Outcomes With Precision Study
Sponsor: University of California, San Francisco
Summary
This is a national, prospective study designed to investigate the genetic etiologies of non-immune hydrops fetalis (NIHF) and other birth defects. At least half of prenatally diagnosed NIHF cases remain of unknown etiology after standard work up, and a substantial proportion of other birth defects remain of unknown etiology as well. The investigators are performing exome sequencing (ES) for the affected fetus or neonate in unexplained cases, as well as enrolling cases with a genetic explanation to represent the full spectrum of diseases underlying NIHF and other birth defects.
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
500
Start Date
2018-10-11
Completion Date
2027-02
Last Updated
2026-02-05
Healthy Volunteers
No
Conditions
Interventions
Exome sequencing
Expansive genetic test performed for affected fetus or neonate.
Locations (1)
University of California, San Francisco
San Francisco, California, United States