Clinical Research Directory

Inclusion Criteria: * Ages 12-35 * Antipsychotic naïve or antipsychotic treatment for equal to or less than 2 weeks within the past 3 months; the minimum AP dose will be left to the discretion of the PI * DSM-5 diagnosis (using SCID-IV-TR with supplemental questions from SCID-5 or SCID-5) of schizophrenia, schizoaffective disorder, schizophreniform disorder, delusional disorder, and brief psychotic disorder, psychotic disorder NOS. and/or antipsychotic treatment for schizophrenia, schizoaffective disorder, or other specified schizophrenia spectrum and other psychotic disorder. Exclusion Criteria: * Previous antipsychotic treatment (greater than two weeks within the preceding 3 months) * Presence of DSM-5 diagnosis which is not schizophrenia, schizoaffective disorder, or other specified schizophrenia spectrum and other psychotic disorder * Use of any other medications for treatment of lipids, glucose, or weight as deemed to be clinically significant by the PI * Use of other medications where the dose has changed within the past 6 weeks which are deemed by the PI to be clinically significant * Pregnancy * Eating disorder - active or previous * Major medical or surgical event within the preceding 3 months * Acute suicidal risk * Irritable bowel disease, Crohn's disease, and/or diverticulitis/diverticulosis * Type I diabetes, kidney/liver disease, and/or cancer * Organ transplant * Moderate to severe alcohol use , use of street drugs, and/or cannabis use (as deemed by PI) * Immunosuppressants and/or anti-inflammatory medications * Antibiotic/probiotic use within past 4 weeks * Any other medical conditions or lifestyle habits deemed by the PI to impact the integrity of the sample/microbiota