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Dietary Phytoestrogens as Risk Factors for Systemic Lupus Erythematosus
Sponsor: University Hospital, Bordeaux
Summary
The study aims at determining if dietary phytoestrogens can be risk factors for Systemic Lupus Erythematosus (SLE). Dietary enquiry and phytoestrogens measurements will be performed in blood and urine of patients with SLE in an active phase of the disease, in patient with other autoimmune diseases and in healthy volunteers. Subjects will be premenopausal women and when possible at a define stage of the menstrual cycle. Free blood estradiol will be assayed as a confounding risk factor.
Official title: Dietary Phytoestrogens in Blood and Urine of Female Patient With Acute Systemic Lupus Erythematosus
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
63
Start Date
2018-11-26
Completion Date
2023-06-26
Last Updated
2026-05-14
Healthy Volunteers
Yes
Interventions
blood sample
25 ml whole blood for Peripheral blood mononuclear cell (PBMC) and monocytes isolation
urine sample
10 ml
food questionnaire
dietary habit enquiry and a 48h dietary
hair
lock of hair
Locations (1)
CHU de Bordeaux - service de médecine interne
Pessac, France