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RECRUITING
NCT03422302
NA

Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

Sponsor: M.D. Anderson Cancer Center

View on ClinicalTrials.gov

Summary

This pilot phase I/II trial studies how well a continuous positive airway pressure device or deep inspiration breath hold works in reducing tumor movement in patients undergoing stereotactic body radiation therapy (SBRT) for lung cancer. The continuous positive airway pressure device works by blowing air into the lungs while patients wear a face mask or nozzle to help expand their airways and lungs. Deep inspiration breath hold is a standard technique that uses active breath-holding to restrict movement of the body. Using a continuous positive airway pressure device may work better than deep inspiration breath hold in lowering the amount of tumor movement during stereotactic radiation body therapy.

Official title: Measuring the Effectiveness of a Continuous Positive Airway Pressure (CPAP) Device to Reduce Tumor Motion and Increase Lung Volume Expansion in Patients Undergoing Stereotactic Body Radiotherapy (SBRT) for Tumors That Move With Respiration

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2018-03-16

Completion Date

2028-05-31

Last Updated

2026-01-27

Healthy Volunteers

No

Interventions

DEVICE

Biphasic Positive Airway Pressure

Receive BiPAP

PROCEDURE

Computed Tomography

Undergo CT simulation scans

PROCEDURE

Continuous Positive Airway Pressure

Receive CPAP

PROCEDURE

Deep Inspiration Breath Hold

Complete DIBH

RADIATION

Radiation Therapy Treatment Planning and Simulation

Undergo CT simulation scans

RADIATION

Stereotactic Body Radiation Therapy

Undergo SBRT

Locations (1)

M D Anderson Cancer Center

Houston, Texas, United States