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Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer
Sponsor: M.D. Anderson Cancer Center
Summary
This pilot phase I/II trial studies how well a continuous positive airway pressure device or deep inspiration breath hold works in reducing tumor movement in patients undergoing stereotactic body radiation therapy (SBRT) for lung cancer. The continuous positive airway pressure device works by blowing air into the lungs while patients wear a face mask or nozzle to help expand their airways and lungs. Deep inspiration breath hold is a standard technique that uses active breath-holding to restrict movement of the body. Using a continuous positive airway pressure device may work better than deep inspiration breath hold in lowering the amount of tumor movement during stereotactic radiation body therapy.
Official title: Measuring the Effectiveness of a Continuous Positive Airway Pressure (CPAP) Device to Reduce Tumor Motion and Increase Lung Volume Expansion in Patients Undergoing Stereotactic Body Radiotherapy (SBRT) for Tumors That Move With Respiration
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2018-03-16
Completion Date
2028-05-31
Last Updated
2026-01-27
Healthy Volunteers
No
Conditions
Interventions
Biphasic Positive Airway Pressure
Receive BiPAP
Computed Tomography
Undergo CT simulation scans
Continuous Positive Airway Pressure
Receive CPAP
Deep Inspiration Breath Hold
Complete DIBH
Radiation Therapy Treatment Planning and Simulation
Undergo CT simulation scans
Stereotactic Body Radiation Therapy
Undergo SBRT
Locations (1)
M D Anderson Cancer Center
Houston, Texas, United States