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Alternation in the Human Microbiome With Commonly Used Topical Medications
Sponsor: University of California, Davis
Summary
The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: 1. Investigate whether ketoconazole cream, a commonly used topical antifungal, causes alterations in the human skin microbiome with short-term use. 2. Investigate whether desonide 0.05 % ointment, a commonly used low potency topical steroid, alters the human microbiome with short-term use.
Official title: Alterations in the Human Microbiome With Commonly Used Topical Medications
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2013-01-28
Completion Date
2026-09-28
Last Updated
2026-02-20
Healthy Volunteers
Yes
Conditions
Interventions
Desonide 0.05%
Desonide 0.05% ointment topically twice daily for two weeks
Ketoconazole 2%
Ketoconazole 2% cream topically twice daily for two weeks
Locations (1)
University of California, Davis, Department of Dermatology
Sacramento, California, United States