Clinical Research Directory

Inclusion Criteria: * • Primary acute proximal ACL rupture (MRI and per-operative confirmation): 3-digit ACL rupture classification, type A (supplement 1) * Between 18-50 years, male or female * Randomization and surgery within 4 weeks after the ACL rupture (Study 1) * Randomization and surgery between 5-12 weeks after the ACL rupture (Study 2) * The ACL remnant is suitable for repair in the three treatment groups: the distal ACL remnant must be in contact with the proximal remnant/femoral condyle for at least 75% (per-operative confirmation) * The patient is mentally and verbally capable of participating in the study. * Written informed consent (according to the International Conference on Harmonisation (ICH)-GCP Guidelines). Exclusion Criteria: * • Known posterior cruciate ligament (PCL) and/or posterolateral ligamentous complex (PLC), lateral collateral ligament (LCL) or medial collateral ligament (MCL) grade 3 injury. * Known osseous fractures that could impair revalidation and/or ACL repair * Patients with neurological disorders or systemic diseases * Patients with trauma/fractures in the lower limb in the past 6 months that could influence rehabilitation * Non-sportive patients with a Tegner score of \<3: these patients could probably counteract instability complaints with intensive physiotherapy. * Any inflammatory disease, Rheumatoid Arthritis (RA), Spondyloarthropathy (SpA), active malignancy * Patient not suited for intervention due to lack of mobility, meaning not achieving 90° of flexion before surgery.