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ACTIVE NOT RECRUITING
NCT03446521

AGRA Before and After Liver Transplantation

Sponsor: Medical University of Graz

View on ClinicalTrials.gov

Summary

The immune system is impaired in liver cirrhotic patients, which is associated with a high risk for bacterial infections and worse outcome. A novel biomarker, acellular growth retardation ability (AGRA), can predict the development of severe infections in patients with liver cirrhosis and therefore identify patients at risk. It is still unclear, how this biomarker develops after liver transplantation and how valid its predictions are for post-operative infections. Therefore, AGRA will be measured before and after liver transplantation and predictive merit of AGRA for post-transplant infections will be tested.

Official title: Humoral Immune Status in Patients With Liver Cirrhosis Before and After Liver Transplantation

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

76

Start Date

2018-07-06

Completion Date

2026-12

Last Updated

2025-02-11

Healthy Volunteers

No

Conditions

Locations (1)

Department of Internal Medicine, Medical University of Geraz

Graz, Austria