Clinical Research Directory

Inclusion Criteria: * Cultural, histopathological, antigen or DNA evidence of invasive fungal infection with Candida species. * Hepatosplenic candidiasis with signs of disseminated Candida infection without culture, histological or microscopic evidence * Case control Matching procedure for controls: In part, controls will be included at the same hospitals that include cases (i.e. each one control per case, both in the same hospital). Controls will be matched by demographics, underlying diseases and risk factors as well as duration of hospitalization Exclusion Criteria: \- Colonization or other non-invasive infection, including superficial skin infections, candiduria without dissemination or Candida spp. in stool.