Clinical Research Directory

Inclusion Criteria: * Male (or transgender male person at birth) * At least 18 years old * HIV-seronegative * Having had at least one anal sex episode with another man within the previous 6 months * Having at least one of the following criteria: * Have a sexual partner (male or female) infected with HIV without evidence of virological suppression * Have had anal or vaginal sex episodes without condoms with more than one partner within the previous 6 months * Have had a sexually-transmitted infection (STI) within the previous 6 months (syndromic or biological approach, or mentioned by the participant) * Have received post-exposure prophylaxis for HIV within the previous 6 months * Wishing to reinforce its means of prevention through the use of PrEP * Accepting to participate in the study and signing the informed consent form Exclusion Criteria: * Clinical manifestations suggesting a primary HIV infection * Recent probable HIV exposure * Creatinine clearance \<60 mL/min calculated according to the Cockroft \& Gault formula * Positive or undetermined HBsAg * Allergy or contraindication to any of the components of PrEP * Participation in another biomedical and/or behavioral study on HIV or STIs (excluding CohMSM) * Disability of the person making it difficult, if not impossible, to participate in the study or understanding of the information given to him * Predictable non-compliance with the protocol (geographical distance, non-compliance with monitoring or other reasons)