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Effectiveness of Contrast-Enhanced Ultrasound
Sponsor: Children's Hospital of Philadelphia
Summary
The purpose of the study is to generate pilot data describing test characteristics of contrast enhanced ultrasound in young children with concern for abdominal trauma. The primary objective in this study is to determine the sensitivity and specificity of contrast-enhanced ultrasound (CEUS) compared to abdominal Computed Tomography (CT) in the detection of abdominal solid organ injury in young children \< 8 years of age with concern for blunt abdominal trauma.
Official title: Clinical Effectiveness of Contrast-Enhanced Ultrasound in the Evaluation of Blunt Abdominal Trauma in Young Children
Key Details
Gender
All
Age Range
0 Years - 7 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2018-05-09
Completion Date
2026-12
Last Updated
2025-12-24
Healthy Volunteers
Yes
Interventions
Contrast-Enhanced Ultrasound using Lumason
Subjects will undergo a contrast enhanced ultrasound (CEUS) during which a standard greyscale abdominal ultrasound is performed first followed by injection of intravenous contrast with Lumason, and completion of contrast-enhanced ultrasound
Locations (1)
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States