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Developing Non-Communicable Disease Registries in Africa : A Step Towards Providing Quality Data for Improving Patient Outcomes
Sponsor: Memorial Sloan Kettering Cancer Center
Summary
This umbrella protocol seeks to develop robust data registries for non-communicable diseases (NCDs) in sub-Saharan Africa (SSA) with the aim of providing accurate and comprehensive data for the evaluation of such diseases in sub-Saharan African countries.Healthy volunteers will be included in the study for comparison. Additionally, the investigators aim to describe the gut microbiome community diversity of a cohort of community dwelling Nigerians and compare with CRC patients in Nigerian and at MSK. We will collect stool for microbiome and metabolomic analysis from community dwelling persons in the catchment area of ARGO facilities in Nigeria while contemporaneously administering an extensive medical and environmental exposure questionnaire.
Official title: Developing Non-Communicable Disease Registries in Africa: A Step Towards Providing Quality Data for Improving Patient Outcomes
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
6990
Start Date
2018-03-16
Completion Date
2027-03
Last Updated
2026-03-05
Healthy Volunteers
Yes
Conditions
Interventions
Questionnaire forms
The questionnaires will include information such as socio-demographic data, risk factors, disease specific data, investigation and treatment details as well as findings during followup. Particular reference will be made to outcome measures such as local and distant recurrence, survival and mortality.
Bio-specimen samples
Samples can include tissue, blood, urine, saliva, hair and nail clipping.
Locations (14)
Memorial Sloan Kettering Cancer Center
New York, New York, United States
National Hospital of Abuja (Data collection only)
Abuja, Central Business District, Nigeria
Lagos State University Teaching Hospital
Idi Araba, Lagos, Nigeria
Olabisis Onabanjo University Teaching Hospital
Sagamu, Ogun State, Nigeria
Federal Medical Centre Owo
Owo, Ondo State, Nigeria
University College Hospital
Ibadan, Oyo State, Nigeria
Ladoke Akintola University of Technology
Ogbomoso, Oyo State, Nigeria
University Of Nigeria Teaching Hospital (UNTH) Ituku-Ozalla Enugu
Enugu, Nigeria
Lagos State University Teaching Hospital
Ikeja, Nigeria
Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC)
Ile-Ife, Nigeria
University of Ilorin Teaching Hospitals
Ilorin, Nigeria
University of Maiduguri Teaching Hospital (Data collection only)
Maiduguri, Nigeria
Ondo State Trauma and Surgical Centre
Ondo, Nigeria
Federal Medical Centre Owo
Owo, Nigeria