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Tapering From Long-term Opioid Therapy in Chronic Pain Population. Randomized Controlled Trial With 12 Months Follow up
Sponsor: Lund University Hospital
Summary
This randomized controlled study compares tapering of long-term opioid therapy in a population with chronic non-cancer pain with control group constituted of waiting list. Half of participants receives intervention at baseline and the other half are controls but receives intervention after 4 months. Ethical approval to follow up excluded participants denying tapering at baseline.
Official title: Tapering of Prescribed Opioids in Patients With Long-term Non-malignant Pain - Efficacy and Effects on Pain, Pain Cognitions, and Quality of Life (TOPIO): a Study Protocol for a Randomized Controlled Clinical Trial With a 12 Month Follow-up
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
140
Start Date
2018-03-22
Completion Date
2025-12-30
Last Updated
2025-03-07
Healthy Volunteers
No
Interventions
Tapering
Tapering with follow up by nurse at weekly basis in beginning of tapering. Tapering in an outpatient setting. Follow-up to doctor after four months.
Locations (3)
Lund University Hospital
Lund, Skåne County, Sweden
Paincentre Sahlgrenska University Hospital
Gothenburg, Västra Götaland County, Sweden
Pain and rehabilitation centre Linköping University Hospital
Linköping, Östergötland County, Sweden