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Surveillance and Tracking the Outcomes of Chronic Latent EBV Infection
Sponsor: Huazhong University of Science and Technology
Summary
Immunocompetent subjects with high load of Epstein-Barr virus DNA (EBV-DNA) in peripheral blood will be enrolled and prospectively followed up to track the natural histories of the chronic high load of EBV virus. The primary goal of this study is to explore the association of peripheral high load of EBV with the hematological malignancies, and second goal is to investigate the genetic mechanisms of immune escape and tumorigenesis of chronic EBV infection.
Official title: Study to Surveil and Track the Outcomes of Chronic Latent EBV Infection Based on Healthy Volunteers Undergoing Routine Inspection
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
10000
Start Date
2019-07-01
Completion Date
2029-12-31
Last Updated
2021-02-10
Healthy Volunteers
No
Conditions
Interventions
peripheral EBV-DNA load
No intervention
Locations (1)
Tongji hospital, Tongji medical collage of HUST
Wuhan, Hubei, China