Clinical Research Directory

Inclusion Criteria: TBI Patients * Injury occurred within 30 days * Documented and verified TBI by Glascow coma scal 10-15 and/or Loss of Consciousness \>10 minutes. * Head Computed Tomography at admission. ALL Subjects: * 18 through 60 years of age. * Ability to understand the the willingness to sign a writteninformed consent. * All races and ethnicities will be included; subjects must be able to read and speak either the English or Spanish language. Exclusion Criteria: * Non-traumatic structural brain abnormality identified on head CT. * Metallic foreign bodies on the scalp or cranium which may interfere with MRI acquisitions. * Penetrating TBI. * Significant anatomic distortion of the brain identified on CT images, such as large hematomas, herniation, intraventricular hemorrhage, extensive subarachnoid hemorrhage, hydrocephalus. * Significant polytrauma that would interfere with follow-up and outcome assessment. * Patients on psychiatric hold. * Major debilitating mental health disorders including, but not limited to schizophrenia and bipolar disorder that would limit compliance with study requirements. * Major debilitating neurological disease including, but not limited to, stroke, CVA, dementia and tumor that would limit compliance with study requirements. * Under influence of illicit drugs which are known to alter brain physiology/metabolism including, but not limited to cocaine, lysergic acid diethylamide (LSD), and marijuana at the time of MRI/MRSI scanning. * Any contraindication per MRI Screening Form including * Implants contraindicated at 3T, pacemakers * Implantable Cardioverter Defibrillator (ICD) * Claustrophobia * Prisoners or patients in custody. * Medically unstable including * Heart failure * Severe left ventricular outflow tract (LVOT) obstruction * Unstable angina * Pregnancy * Lactating * Subjects who are receiving any other investigational agents.